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What is CoQ10?
If you’ve heard about CoQ10, or Coenzyme Q10, it’s no surprise. As a supplement, it has become almost as ubiquitous as its more formal name, ubiquinone, would imply. Found naturally in the mitochondria, the engine of all living cells in the body, CoQ10 is essential for the production of energy.*1
CoQ10 and the Heart
Because the heart beats 24 hours a day, 365 days a year, cardiac cells require large amounts of uninterrupted energy. They have a greater number of mitochondria and subsequently more CoQ10 than any other type of cell.2,3 CoQ10 supports healthy cardiovascular function and exercise endurance.*
Individuals who are prescribed statin medications also need to be aware that these cholesterol-lowering medications have been shown to decrease the body’s supply of CoQ10.4,5,6 Statins act to inhibit the enzymes that are involved in cholesterol production, which takes place in the liver. Unfortunately, they also inhibit the production of CoQ10 in the process.
CoQ10 and the Brain
The brain requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital.7
Supplementing with CoQ10
Although the body can produce its own supply of CoQ10, there are times when adding supplemental CoQ10 can be important.
When looking for the ideal CoQ10 supplement, look for products that are supported by product-specific research from reputable institutions. Make sure it’s proven to be safe, tolerable, and effective—even at higher doses.
CoQ10 supports heart neurological health and healthy aging in general.* No supplement can take the place of a proper diet rich in whole foods and a lifestyle vibrant with exercise. But the benefits of CoQ10 are worth considering as a part of your daily health regimen–and the evidence of its effectiveness is growing.
1. PDR® for Nutritional Supplements™. 2nd ed. Montvale, NJ: Physician’s Desk Reference Inc; 2008:151-55.
2. Guyton AC, Hall JE. Mitochondria. In: Textbook of Medical Physiology. 9th ed. Philadelphia, Pa: WB Saunders; 1996:16-17.
3. Mol Aspects Med 1997;18 Suppl:S145-S151
4. Proc Natl Acad Sci U S A 1990;87:8931-4.
5. J Clin Pharmacol 1993;33:226-9.
6. Mitochondrion 2007;7 Suppl:S168-74.
7. Pathophysiology: Concepts of Altered Health States. 5th ed. Philadelphia, Pa;Lippincott; 1998:833.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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