“Designed to complement the body’s natural tissue growth and to help support an increase in bone density, Bio-Replenishment turns the clock back on bone and joint health.”  Dr. John Jackson

Bio-Replenishment, in the form of OsteoDenx, is a revolutionary breakthrough in skeletal and joint health.  It is not a vitamin supplement or a chemical drug, it contains no calcium and it has no side effects. Developed by Dr. A.S. Naidu and a team of scientists it is an entirely new classification that provides the world with a solution to the growing bone and joint challenges.

The United Nations, World Health Organization and more than 40 national governments have publicly acknowledged bone and joint disorders as the chronic care challenge of the 21st century.

  • 10 million Americans have Osteoporosis
  • 34 million Americans have low bone mass
  • 66 million adults have joint related issues.
  • Teenage youth are at risk for osteoporosis.
  • Men are now more likely to get osteoporosis than they are prostate cancer.
  • Bone and joint disease are a leading cause of disability affecting over 16 million adults in the U.S.


These statistics lead millions to search out Prescription Drugs that are designed to inhibit natural bone turnover and the necessary calcium withdrawals from exiting bones.  This leaves other bodily systems that require calcium from bones to suffer, and bones may become denser but are weaker.  Some of the medications may even create a brittle bone matrix or spontaneous fractures, leading to the phrase that, ‘it’s not that they will fall and break their bones, yet that they will break their bones and fall.’

Known Side Effects of Prescription Bone Drugs:

  • Esophogeal Cancer
  • Altered Taste
  • Numbness
  • Mental Irritability
  • Dental Problems
  • Bone Necrosis (death)
  • Seizures
  • Anemia
  • Blood Clotting Disorders
  • Muscle, Joint, Bone Pain
  • Heartburn
  • Difficulty Swallowing
  • Decreased Joint Mobility
  • Eye Problems
  • Skin Rash
  • Heartburn


Because calcium is the main mineral lost in osteoporosis, it has been thought that high calcium intake would reduce bone loss. However, research has not borne this out. Instead it shows that high protein intake from meat and dairy sources, robs calcium from the bones, even when calcium supplements are being taken.

With Calcium Supplementation alone, much of the ingredients will never reach the intended destination. A large portion of ingested calcium is excreted because the body can only consume enough for it’s immediate needs.

Excess calcium buries itself in artery walls and muscle cells where it contributes to high blood pressure and hardening of the arteries.  It has also been known to form into stones in the bladder and kidney.”

Maintaining strong bones is critically important for good health.  The skeleton is a structural framework that provides protection, flexibility and motion.  In addition, bones serve as a chemical storehouse.

Our bones must continually rebuild themselves and the entire skeletal system is effectively replaced 10 times in the average lifetime.  The ability to rebuild bone diminishes over time.  Age is only one of the factors that can lead to a decrease in bone strength.

Caffeine, alcohol, sugar, soda, acidic lifestyle choices and many medications make significant withdrawals from the skeletal system.  Obesity and overweight also impose stress on the skeletal structure.

Medical authorities caution that bones can weaken with no sign of warning, even at a relatively young age, without proper attention. Physical activity is known to help build up bone, but few receive the exercise they need, and as we’ve seen that alone may not solve the problem.

OSTEODENX promotes both aspects of bone health: the release and absorption of mineral compounds as well as the formation of new bone tissue.

It includes a patent-pending transport system, Syno-Portin that is formulated to support the body’s own natural replenishment of calcium and other minerals.

Syno-Portin enables bone health ingredients to reach the specific target site, the joint area, for improved bioavailability.


  • Promotes the physical process of replacing bone tissue.
  • Supports the optimal balance of minerals within bones and joints.
  • Helps maintain bone density.
  • Supports the structure and the integrity of joint cartilage.
  • Enhances the functionality and improves the availability of the body’s biological material to support the physical processes that keep us alive and healthy.


Bio-Replenishment Technology is based on 20+ years of scientific research, with results published in leading medical and professional journals.

For a complete Bone / Joint Health solution, it is recommended to take OsteoDenx with CalDenx and Lactoferrin Gold 1.8.

CalDenx provides the material needed for bone regeneration and supports bone and the skeletal system.  It is an optimized blend of Calcium with Vitamin D, Folate, Magnesium, Zinc, Copper, Chromium and Boron.

As bone health depends in large part upon the absorption of ingested minerals, the gastrointestinal system plays a major role.

Lactoferrin Gold 1.8 assists in preserving a healthy intestinal tract, helps maintain beneficial bacteria our bodies depend on, supports immune function, enhances the body’s natural antioxidant response, which is responsible for resisting the effects of aging, and contributes to health and total body support

Dr. Narain Naidu, Ph.D. an internationally renowned Medical Microbiologist discovered Bio-Replenishment and developed OsteoDenx, CalDenx and Lactoferrin Gold 1.8.

His discoveries are the basis for the founding of 4 successful Biotech companies and he is on the faculty of universities in Europe, Asia and the United States.

Besides consulting with Government Health Agencies, Pharmaceutical and Biotech enterprises worldwide, he has 100 research publications, 25 book chapters, and 2 best selling reference volumes.

Dr. Naidu helped solve Toxic Shock Syndrome and the E-Coli problem in the US beef industry.  He has been Director for the Center for Antimicrobial Research, past Director of www.nterminus.com on the short list for the Nobel Prize and most recently appointed Advisor to the Prime Minister of India for Health Education.  Dr. Naidu has given Nikken exclusive rights to OsteoDenx, CalDenx and Lactoferrin Gold 1.8.

Link To Purchase OsteoDenx®

Link To Purchase OsteoDenx®






“I love using Nikken’s natural alternative to the pharmaceutical companies prescription drugs for my bone health.”