Summary In part 1 of this 2 part series the paper entitled: Designing a polarity therapy protocol: Bridging holistic, cultural, and biomedical models of research, presented rationale for the design and development of a standardized Polarity therapy protocol for the treatment of dementia caregivers. In this second part, the bodywork protocol is presented with allopathic and esoteric anatomical locations. This protocol was designed as one approach to developing a standardized intervention that would maximize the reduction of stress, depression and anxiety and enhance well-being and quality of life in the recipients. There are many options for choosing points and locations for protocol and these must first address acceptability by the research participant and capacity of the therapist to repeatedly apply the protocol. The potential for pleasurable and a profound stress reduction response was informed by anecdotal data and clinical observation and this also informed the selection of points. Finally, the polarity paradigm is derived from the balancing of the gunas, and this also informed the choice of points and contacts.